Isotopically Labeled Compounds
Medchemexpress LLC Sphingosine-1-phosphate (S1P) | 26993-30-6 | 99.5% | 379.47 | 25 MG
Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. It functions as an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. This lipid mediator stimulates DNA synthesis, cell proliferation, and migration.
- Agonist of S1P1-5 receptors and a ligand of GPR3, GPR6, and GPR12.
- Functions as an intracellular second messenger.
- Mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors.
- Important lipid mediator.
- Stimulates DNA synthesis, cell proliferation, and migration.
- For research use only.
Medchemexpress LLC Oxprenolol-d7 hydrochloride | 1189649-47-5 | 98.25% | 5 MG
Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Oxprenolol-d7 hydrochloride | 1189649-47-5 | 98.3% | 1 MG
Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
- Can be used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes as tracers for quantitation during drug development.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical PalmItoyl EthnolamIde-d4 1mg
An internal standard for the quantification of palmitoyl ethanolamide by GC- or LC-MS
Medchemexpress LLC 2,2'-bipyridine-d8 | 32190-42-4 | MFCD00190432 | 99.3% | 164.24 g·mol⁻¹ | C10D8N2 | 10 MG
2,2′-Bipyridine-d8 is the deuterium-labeled isotopologue of 2,2′-bipyridine supplied as a white to off-white solid for analytical and synthetic chemistry. It is intended for use as a tracer or internal standard in quantitative NMR, GC-MS, and LC-MS workflows, providing consistent isotopic labeling for accurate spectral and mass analyses.
- Deuterium-labeled (d8) isotopologue for isotope-dilution and tracing experiments.
- High stated purity of 99.33% for reliable analytical performance.
- Molecular formula C10D8N2 and molecular weight 164.24 g·mol⁻¹.
- Soluble in DMSO (~100 mg/mL) with ultrasonic assistance for solution preparation.
- Stable when stored as a powder at -20°C for long-term storage or 4°C for shorter term.
- Suitable as an internal standard for quantitative NMR, GC-MS, and LC-MS analyses.
Medchemexpress LLC Thiocolchicine-d3 1mg | 1314417-95-2 | 418.52 | C22H22D3NO5S | 1 MG
Thiocolchicine-d3 is a deuterium-labeled derivative of thiocolchicine used for research applications. It inhibits tubulin polymerization (reported IC50 = 2.5 μM; Ki = 0.7 μM), induces apoptosis, and can be used as a tracer or internal standard for quantitative NMR, GC-MS, or LC-MS.
- Deuterium-labeled tracer/internal standard for analytical quantitation.
- Tubulin polymerization inhibitor with reported IC50 = 2.5 μM.
- Reported Ki for tubulin binding of 0.7 μM.
- High purity (≥99.0%).
- Small pack sizes suitable for analytical applications.
- Store protected from light; stable at -80°C in solvent for up to 6 months.
Cayman Chemical ImIdacloprId-d4 1mg
An internal standard for the quantification of imidacloprid by GC- or LC-MS
Medchemexpress LLC i-Inositol-d1 | 99.5% | 1 MG
i-Inositol-d1 is a stable isotope of inositol, with a molecular formula of C6H11DO6 and a molecular weight of 181.16. It appears as a white to off-white solid.
- High purity (HPLC): 99.46%
- High isotopic enrichment: 98%
- Suitable for research use only
- Stable in powder form for up to 3 years at -20°C
- Stable in solvent for up to 6 months at -80°C
Medchemexpress LLC Betaine-d9 chloride | 285979-85-3 | 99.7% | 162.66 g·mol⁻¹ | C5H3D9ClNO2 | 10 MG
Betaine-d9 chloride is the deuterium-labeled analogue of betaine chloride used as a stable isotope research standard for quantitative mass spectrometry and tracer studies.
- Suitable as an internal standard for mass spectrometry.
- Deuterium-labeled tracer for isotope-labeling experiments.
- High chemical and isotopic purity for accurate quantitation.
- Supplied as a solid chloride salt for analytical workflows.
- Available in small mg-scale pack sizes for research use.
Medchemexpress LLC Tenuazonic acid-d13 | 2714417-30-6 | 99.2% | 210.31 | C10H2D13NO3 | 1 MG
Tenuazonic acid-d13 is a deuterium-labeled analytical standard of tenuazonic acid supplied as a white to off-white solid for research applications. It is used primarily as an internal standard or tracer in mass spectrometry and quantitative analysis, and is provided with manufacturer COA and SDS documentation for quality and safety.
- Deuterium-labeled internal standard for mass spectrometry quantification
- Molecular formula C10H2D13NO3 and molecular weight 210.31
- High purity: 99.2%
- Appearance: white to off-white solid
- Storage: powder -20°C (stable for 3 years); in solvent -80°C (6 months), -20°C (1 month)
- COA and SDS available for batch-specific quality and handling information
Medchemexpress LLC Melperone-d4 (hydrochloride) | 1219798-80-7 | 99.8% | 500 UG
Melperone-d4 hydrochloride is the deuterium labeled Melperone hydrochloride. Melperone hydrochloride is a butyrophenone with atypical antipsychotic properties. It is a multireceptor antagonist with Kds of 102 nM, 180 nM, 180 nM, and 150 nM for 5-HT2A, dopamine D2, α1-adrenergic, and α2-adrenergic receptors, respectively. Melperone hydrochloride has weak binding to histamine H1, 5-HT2C, 5-HT1A, 5-HT1D, and muscarinic receptors, with Kd values of 580 nM, 2100 nM, 2200 nM, 3400 nM, >10000 nM, respectively. It is also a CYP2D6 inhibitor and can be used for the study of schizophrenia and agitation in the elderly.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Chlorhexidine-d8 dihydrochloride | 2012598-75-1 | 95.7% | 1 MG
Chlorhexidine-d8 dihydrochloride is a deuterium labeled form of Chlorhexidine dihydrochloride, an orally active cationic antimicrobial agent. It targets microbial cell membranes, binding to phospholipids non-specifically to destroy membrane structure and induce leakage of cell contents. It exhibits broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria by interfering with membrane permeability, causing protein precipitation, and disrupting energy metabolism. This leads to rapid inhibition of microbial growth and induction of cell death.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC D-Fructose-13C | 108311-21-3 | 10 MG
D-Fructose-13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants. It is for research use only and not sold to patients.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
![Revvity Health Sciences Inc GLP-1 (7-36), [<sup>125</sup>I]-, 10µCi (370kBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2307162.jpg-250.jpg)
Revvity Health Sciences Inc GLP-1 (7-36), [125I]-, 10µCi (370kBq)
GLP-1 (7-36), [125I]-, 10µCi (370kBq)
Medchemexpress LLC Tacrolimus-13C,d2 | 1356841-89-8 | 98.4% | 807.02 | 1 MG
Tacrolimus-13C,d2 is a 13C-labeled and deuterium-labeled form of Tacrolimus, a macrocyclic lactone. It inhibits calcineurin phosphatase by forming a complex with FKBP, which leads to immunosuppressive properties by inhibiting T-lymphocyte signal transduction and IL-2 transcription. This compound can be used as a tracer and an internal standard for quantitative analysis.
- Labeled with 13C and deuterium
- Inhibits calcineurin phosphatase
- Possesses immunosuppressive properties
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS